Thygeson’s superficial punctate keratitis

Thygeson’s Superficial Punctate Keratitis- Case Report and Review

Thygeson’s superficial punctate keratitis is a subtle, chronic and bilateral condition of the corneal epithelium, typically manifests with acute exacerbations and remissions. The etiology remains uncertain, despite the possibility of viral etiology was suspected. Topical steroid administration is useful in aborting an acute phase; but steroid induced cataract and glaucoma developed on long term...

A Survey of Superficial Punctate Keratitis in Tasmania with the Record of a Mild Epidemic.

Morphology of experimental vaccinial superficial punctate keratitis--a scanning and transmission electron microscopic study.

Rabbit corneas infected with vaccinia virus were studied by scanning electron microscopy. The earliest detectable lesion consisted of tiny punctate epithelial pits lined by the intact superficial layers of the epithelium. These lesions were presumed produced by the dissolution of the wing cells with inward collapse of the overlying superficial layer. Examination of more advanced and severe lesi...

Long-term topical cyclosporin A therapy in Thygeson's superficial punctate keratitis: a case report

PURPOSE To describe a patient with Thygeson's superficial punctate keratitis successfully treated with long-term cyclosporin A. CASE PRESENTATION A 15-year-old boy presented with long-term ocular symptoms of foreign body sensation, burning, irritation, tearing, and transient photophobia. One year's treatment with steroidal agents had led to only partial improvement. Clinical and laboratory ev...

In vivo observation of Langerhans cells by laser confocal microscopy in Thygeson's superficial punctate keratitis

PURPOSE To characterize the cornea of individuals with Thygeson's superficial punctate keratitis (TSPK) at the cellular level by laser confocal biomicroscopy. METHODS Both corneas of three patients with TSPK referred to Yamaguchi University Hospital were imaged with a laser confocal biomicroscope. Morphological changes were evaluated for each layer of the cornea. RESULTS The number of Lange...